What is Peptide Synthesis?
Peptide synthesis involves producing peptides, which are compounds where multiple amino acids are linked via amide bonds (peptide bonds). The peptide bond forms through the condensation reaction of the amino group of one amino acid with the carboxylic acid of another amino acid.
Raleigh Peptide Synthesis Capabilities
Our Custom Peptide Synthesis laboratory can synthesize and purify synthetic peptides in either R&D or GMP environments and aseptically fill the peptides in our cGMP facility*.
We offer peptide synthesis services for manufacturing normal peptides and custom modified peptides up to 12-15 amino acids in length to meet your specifications.
We utilize solid-phase peptide synthesis or solution-phase chemistry to manufacture your custom peptides.
Pre- or post-synthesis operations can integrate natural amino acids, modified amino acids, and unnatural amino acids into the peptide sequence. Post-synthesis modifications encompass biotinylation, peptide conjugation, KLH conjugation, linker attachment, and other customized modifications to tailor the peptide properties according to specific project requirements. These versatile operations ensure flexibility and customization in peptide design and functionality.
We employ preparative HPLC to isolate the desired peptide during synthesis, followed by analysis using reverse-phase HPLC to confirm purity. Depending on your research requirements, Raleigh Molecular can provide peptides with a purity range from 70% to 98%. Mass spectrometry is utilized to verify the mass accuracy of the synthesized peptide, ensuring precise characterization of the final compound. These analytical techniques guarantee the quality and accuracy of the synthesized peptides for your specific applications.
Purification processes are efficiently carried out using our diverse range of HPLC systems, capable of a flow rate of 200 mL/min. Our HPLC columns have capacities of up to 2.2 liters, enabling rapid and effective purification of synthesized peptides and ensuring high-quality outputs for your research or production needs.
We take pride in our knowledge and expertise, allowing us to provide custom peptide synthesis services to our clients with confidence. Raleigh Molecular is renowned for high-quality products and technical services, and we stand behind the quality of our work. All peptides are manufactured to the highest quality standards right here in our North American facilities, ensuring reliability and consistency in every batch.
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